Nature Communications (Sep 2022)

Phosphorylcholine-conjugated gold-molecular clusters improve signal for Lymph Node NIR-II fluorescence imaging in preclinical cancer models

  • Ani Baghdasaryan,
  • Feifei Wang,
  • Fuqiang Ren,
  • Zhuoran Ma,
  • Jiachen Li,
  • Xueting Zhou,
  • Lilit Grigoryan,
  • Chun Xu,
  • Hongjie Dai

DOI
https://doi.org/10.1038/s41467-022-33341-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Fluorescent tracers facilitate the identification and subsequent collection of tumour draining lymph node biopsies, enabling important clinical assessment. Here, the authors present a molecular gold nanocluster NIR-II fluorescent imaging probe and demonstrate its utility to visualise draining lymph nodes in breast and colon cancer mouse models.