Эпидемиология и вакцинопрофилактика (Apr 2018)

Immunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia

  • A. V. Korneva,
  • V. B. Nikolaev,
  • T. A. Ivanova,
  • V. I. Dubrovina,
  • G. B. Mukhturgin,
  • E. Yu. Markov,
  • T. P. Starovoitova,
  • A. V. Mazepa,
  • T. T. Shkaruba,
  • S. V. Balakhonov

DOI
https://doi.org/10.31631/2073-3046-2018-17-2-46-49
Journal volume & issue
Vol. 17, no. 2
pp. 46 – 49

Abstract

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Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the preparations from F. tularensis urea lysates are not toxic for experimental animals. Besides, CW of F. tularensis А-61 subsp. mediasiatica and F. tularensis B-399 A-Cole subsp. tularensis possess immunogenic activity in experimental tularemia caused by F. tularensis 306 subsp. holarctica.

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