Clinical Reproducibility of the Stone Volume Measurement: A “Kidney Stone Calculator” Study

Abstract

Background: An accurate estimation of the stone burden is the key factor for predicting retrograde intra-renal surgical outcomes. Volumetric calculations better stratify stone burden than linear measurements. We developed a free software to assess the stone volume and estimate the lithotrity duration according to 3D-segmented stone volumes, namely the Kidney Stone Calculator (KSC). The present study aimed to validate the KSC’s reproducibility in clinical cases evaluating its inter-observer and intra-observer correlations. Methods: Fifty patients that harbored renal stones were retrospectively selected from a prospective cohort. For each patient, three urologists with different experience levels in stone management made five measurements of the stone volume on non-contrast-enhanced computed tomography (NCCT) images using the KSC. Results: the overall inter-observer correlation (Kendall’s concordance coefficient) was 0.99 (p p < 0.0001) for each participant. Subgroup analyses showed that the segmentation of complex stones seems to be less reproductible. Conclusions: The Kidney Stone Calculator is a reliable tool for the stone burden estimation. Its extension for calculating the lithotrity duration is of major interest and could help the practitioner in surgical planning.

Keywords

• Kidney Stone Calculator
• renal stone
• segmentation
• volume
• concordance