Sport şi Societate (Dec 2020)
Relationship between post-traumatic stress disorder (PTSD) and oxidative stress, a pubmed approach
Abstract
Post-traumatic stress disorder (PTSD) is a severe anxiety syndrome and oxidative stress may be involved. The objective was to highlight the relationship between PTSD and oxidative stress, in an approach from the PubMed perspective publications. Keywords were selected: PTSD, PTSD and Oxidative stress (PTSD+OS), PTSD and malondialdehyde (PTSD+MDA), PTSD and reactive oxygen species (PTSD+ROS). The PubMed filter chosen was: a) gender (Sex), with sub-filters: male (HM), female (HF), male and female (HM+HF); b) Age with sub-filters: 0-18, 19-44, 45-64, >65 and >80 years. Analysis criteria: total number of publication (N); the average number of publications per year (N/Y). Of the keywords referring to OS, the highest N and N / Y was for PTSD+OS. For PTSD+MDA and PTSD+ROS, N was fluctuating throughout the publication period. For Sex filter, of the key word combinations referring to OS, most publications were for PTDS+OS at M+F. For Age filter, of the key word combinations referring to OS, most publications were for PTSD+OS at 19-44. Conclusions. 1) Studies on PTSD and Oxidative Stress are numerically reduced compared to those for PTSD, but their presence proves interest in research in this direction. 2) Among the keyword combinations referring to oxidative stress, those about PTSD + ROS were more numerous than those for PTSD + MDA, both in terms of publication period and total number of publications, which proves a greater concern for research. regarding ROS. 3) For all keyword combinations were preferred in the research, subjects of both genders and ciu age between 19-44 years, which shows an interest for mature adult subjects. 4) Although studies on the relationship between PTSD and oxidative stress are still numerically low, their number is important, proving a growing interest over time in this field of research.
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