Place of Semisynthetic Penicillins and Macrolides in Antibiotic Therapy for Respiratory Infections in Children

Abstract

The paper presents an overview of the guidelines for the treatment of respiratory infections by the Pediatric Infectious Diseases Society and Infectious Diseases Society of America (2011), the British Thoracic Society (2013) and national ones (Protocol for providing medical care to children in «pediatric pulmonology» specialty, 2005). An algorithm for the empirical antibiotic choice in the treatment of acute respiratory infections in children, depending on the etiology and age is considered. It is shown that amoxicillin is still the agent of choice in pediatric outpatient practice for the treatment of acute bacterial respiratory infections. Alternative therapy — oral amoxicillin clavulanate; in children with allergy to amoxicillin — macrolides. Macrolide antibiotics (oral form) should be prescribed for the treatment of children (primarily schoolchildren and adolescents) with acute respiratory infection caused by atypical pathogens. When choosing a drug, dispersible forms of antibiotics should be preferred: Flemoxin Solutab® (amoxicillin trihydrate), Flemoclav Solutab® (amoxicillin trihydrate + clavulanic acid), Wilprafen® Solutab (josamycin).

Keywords

• аcute respiratory infection
• antibiotics
• dispersible form
• children.