N-(3-Oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-6-phenylimidazo[2,1-b][1,3]thiazole-3-acetamide hemihydrate

Abstract

The title compound, C21H22N4O2S2·0.5H2O, crystallizes with two molecules in the asymmetric unit. The dihedral angles between the phenyl and imidazothiazole ring systems are 19.16 (9) and 21.37 (9)°. In the imidazothiazole ring systems, the cyclohexane rings adopt chair conformations, while the thiazole rings have distorted envelope conformations. The two molecules are stabilized by intramolecular N—H...O, O—H...O and C—H...S interactions and the crystal structure is stabilized by intermolecular N—H...O, O—H...O, C—H...O and C—H...N interactions.