Influence of the Systemic Application of Blue–Green Spirulina platensis Algae on the Cutaneous Carotenoids and Elastic Fibers in Vivo
Maxim E. Darvin,
Sora Jung,
Sabine Schanzer,
Heike Richter,
Elke Kurth,
Gisela Thiede,
Martina C. Meinke,
Juergen Lademann
Affiliations
Maxim E. Darvin
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Sora Jung
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Sabine Schanzer
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Heike Richter
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Elke Kurth
Institute for Food and Environmental Research (ILU e.V.), Arthur-Scheunert-Allee 40-41, Nuthetal 14558, Germany
Gisela Thiede
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Martina C. Meinke
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
Juergen Lademann
Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany
The objective of the study was to investigate the influence of a food supplement rich in antioxidants on the antioxidant status of the skin. For this reason, the blue-green algae Spirulina platensis powder was used for oral application during eight weeks. The effect of oral application of the antioxidant-containing Spirulina platensis on characteristic skin aging parameters, e.g., concentration of cutaneous carotenoids and the collagen/elastin index (SAAID), was investigated in vivo. A significant average increase from 2.67 ± 0.86 arb. units to 3.25 ± 0.93 arb. units (p < 0.001) in the cutaneous carotenoid concentration was detected subsequent to oral application of the carotenoid-containing Spirulina platensis powder, showing a significant improvement of the antioxidant status of the skin. A slight but not significant increase (p = 0.33) in the dermal SAAID mean values was measured from −0.54 ± 0.11 to −0.51 ± 0.11 subsequent to oral intake of Spirulina platensis powder.
