mBio (Jun 2021)

Outer Membrane Vesicles of Vibrio cholerae Protect and Deliver Active Cholera Toxin to Host Cells via Porin-Dependent Uptake

  • Franz G. Zingl,
  • Himadri B. Thapa,
  • Martina Scharf,
  • Paul Kohl,
  • Anna M. Müller,
  • Stefan Schild

DOI
https://doi.org/10.1128/mBio.00534-21
Journal volume & issue
Vol. 12, no. 3

Abstract

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Cholera is still a massive global health burden because it causes large outbreaks with millions of infections and thousands of deaths every year. Several studies have contributed to the knowledge of this pathogen, although key parts are still missing.