Incidence of thyroid pathology in the Ozyorsk population exposed to technogenic radiation exposure in childhood

Abstract

The assessment of thyroid pathology incidence among Ozyorsk population, born in 1934-1963, who were exposed to technogenic radiation exposure in childhood, predominantly iodine-131, was performed based on the screening study of 12,504 individuals. The thyroid screening algorithm included examination by a physician, ultrasound screening, laboratory tests on hormonal status and autoimmunity, examination by an endocrinologist; council of physicians for verification of uncertain cases. The thyroid pathology was found in 34.4% of individuals from the study cohort. For the first time, 70.4% of all registered thyroid diseases were detected. The nodular goiter prevailed among other thyroid pathologies. The single-nodular goiter incidence was significantly higher than that of multinodular goiter, both for males and females. The incidence of thyroid pathology was significantly dependent on gender, attained age at the time of screening, and hereditary predisposition.

Keywords

• incidence
• thyroid
• screening
• technogenic radiation exposure
• radioactive iodine