Acta Biomedica Scientifica (May 2012)
MODERN APPROACH ТО DIAGNOSTCS AND TREATMENT OF PATHOLOGICAL HYPERPROLACTINEMIA
Abstract
Hyperprolactinemia is one of the most frequent neuroendocrinal disorders and consequently questions of diagnostics and treatment of this syndrome continue to remain actual. Diagnostics of hyperprolactinemia is not the simple task demanding not only determination of the prolactin levels, but also measurement of its fractions with an assessment of the bioactive prolactin levels, careful studying of the anamnesis, an exception of various somatic, endocrine and neuroendocrinal disturbances. Treatment of a pathological hyperprolactinemia demands the differentiated approach taking into account clinical and biochemical data and radiological data. A leading method of treatment is medical therapy by agonists of dopamin receptors. Diagnostics and treatment of hyperprolactinemia must be based on modern evidence-based guidelines.