Revisited diagnostics of true (acantholytic) pemphigus

Abstract

True (acantholytic) pemphigus is an autoimmune disease characterized by blisters and erosions in the skin and/or mucous tunics. True (acantholytic) pemphigus can be diagnosed based on an assessment of clinical manifestations and results of cytology, histology and immunology tests. The current diagnostics methods are characterized by certain advantages and shortcomings yet none of them has 100% sensitivity and specificity. To diagnose pemphigus, a complex of studies is needed taking into consideration the body of clinical symptoms and laboratory indices.

Keywords

• истинная (акантолитическая) пузырчатка
• акантолитические клетки
• реакция иммунофлюоресценции
• иммуноферментный анализ
• иммуноблоттинг
• true (acantholytic) pemphigus
• acantholytic cells
• immunofluorescence test
• immune-enzyme assay
• immunoblotting