Scientia Pharmaceutica (Nov 2023)

Natural Products for the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review

  • Saverio Nucera,
  • Rosa Maria Bulotta,
  • Stefano Ruga,
  • Rosamaria Caminiti,
  • Maria Serra,
  • Roberto Bava,
  • Fabio Castagna,
  • Carmine Lupia,
  • Mariangela Marrelli,
  • Filomena Conforti,
  • Giancarlo Statti,
  • Vincenzo Mollace,
  • Ernesto Palma

DOI
https://doi.org/10.3390/scipharm91040053
Journal volume & issue
Vol. 91, no. 4
p. 53

Abstract

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Plants are an untapped natural resource; their secondary metabolites take part in a variety of pharmacological activities, making them an essential ingredient in the synthesis of novel medications and the source of reserve resources in this process. Hepatitis and liver cancer are two conditions that can result from non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition that now affects a significant section of the global population. There is a need for preventative action on predisposing factors. Due to their effectiveness and few side effects, herbal medications are frequently utilized for the prevention and treatment of NAFLD. This review discusses the pathogenetic processes of NAFLD and the evidence brought to support the potential of botanical species and their derivatives in limiting the causes that predispose to the onset of NAFLD.

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