Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report

Abstract

Abstract TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.

Keywords

• acute myeloid leukemia
• genetic counseling
• TP53
• variant of uncertain significance