Nucleoside Di- and Triphosphates as a New Generation of Anti-HIV Pronucleotides. Chemical and Biological Aspects

Abstract

This review provides a short account of the chemical synthesis of nucleoside di- and triphosphates on a historical background, together with the use of this class of compounds as potential pronucleotides in anti-HIV therapy.

Keywords

• nucleoside di- and triphosphates
• anti-HIV pronucleotides
• synthetic strategies
• biological activity