Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020

Maureen Rebecca Smith; Maria Trofimova; Ariane Weber; Yannick Duport; Denise Kühnert; Max von Kleist

doi:10.1038/s41467-021-26267-y

Nature Communications (Oct 2021)

Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020

Maureen Rebecca Smith,
Maria Trofimova,
Ariane Weber,
Yannick Duport,
Denise Kühnert,
Max von Kleist

Affiliations

Maureen Rebecca Smith: Systems Medicine of Infectious Disease (P5), Robert Koch Institute
Maria Trofimova: Systems Medicine of Infectious Disease (P5), Robert Koch Institute
Ariane Weber: Transmission, Infection, Diversification and Evolution Group, Max-Planck Institute for the Science of Human History
Yannick Duport: Systems Medicine of Infectious Disease (P5), Robert Koch Institute
Denise Kühnert: Transmission, Infection, Diversification and Evolution Group, Max-Planck Institute for the Science of Human History
Max von Kleist: Systems Medicine of Infectious Disease (P5), Robert Koch Institute

DOI: https://doi.org/10.1038/s41467-021-26267-y
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

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The true number of infections from SARS-Cov-2 is unknown and believed to exceed the reported numbers by several fold. National testing policies, in particular, can strongly affect the proportion of undetected cases. Here, the authors propose a method that reconstructs incidence profiles within minutes, solely from publicly available, time-stamped viral genomes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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