Nature Communications (Dec 2021)
Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows
- Tim Van Den Bossche,
- Benoit J. Kunath,
- Kay Schallert,
- Stephanie S. Schäpe,
- Paul E. Abraham,
- Jean Armengaud,
- Magnus Ø. Arntzen,
- Ariane Bassignani,
- Dirk Benndorf,
- Stephan Fuchs,
- Richard J. Giannone,
- Timothy J. Griffin,
- Live H. Hagen,
- Rashi Halder,
- Céline Henry,
- Robert L. Hettich,
- Robert Heyer,
- Pratik Jagtap,
- Nico Jehmlich,
- Marlene Jensen,
- Catherine Juste,
- Manuel Kleiner,
- Olivier Langella,
- Theresa Lehmann,
- Emma Leith,
- Patrick May,
- Bart Mesuere,
- Guylaine Miotello,
- Samantha L. Peters,
- Olivier Pible,
- Pedro T. Queiros,
- Udo Reichl,
- Bernhard Y. Renard,
- Henning Schiebenhoefer,
- Alexander Sczyrba,
- Alessandro Tanca,
- Kathrin Trappe,
- Jean-Pierre Trezzi,
- Sergio Uzzau,
- Pieter Verschaffelt,
- Martin von Bergen,
- Paul Wilmes,
- Maximilian Wolf,
- Lennart Martens,
- Thilo Muth
Affiliations
- Tim Van Den Bossche
- VIB - UGent Center for Medical Biotechnology, VIB
- Benoit J. Kunath
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Kay Schallert
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Stephanie S. Schäpe
- Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ GmbH
- Paul E. Abraham
- Biosciences Division, Oak Ridge National Laboratory
- Jean Armengaud
- Département Médicaments et Technologies pour la Santé (DMTS), Université Paris Saclay, CEA, INRAE, SPI
- Magnus Ø. Arntzen
- Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU)
- Ariane Bassignani
- INRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay
- Dirk Benndorf
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Stephan Fuchs
- Bioinformatics Unit (MF1), Department for Methods Development and Research Infrastructure, Robert Koch Institute
- Richard J. Giannone
- Biosciences Division, Oak Ridge National Laboratory
- Timothy J. Griffin
- Department of Biochemistry Molecular Biology and Biophysics, University of Minnesota
- Live H. Hagen
- Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU)
- Rashi Halder
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Céline Henry
- INRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay
- Robert L. Hettich
- Biosciences Division, Oak Ridge National Laboratory
- Robert Heyer
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Pratik Jagtap
- Department of Biochemistry Molecular Biology and Biophysics, University of Minnesota
- Nico Jehmlich
- Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ GmbH
- Marlene Jensen
- Department of Plant & Microbial Biology, North Carolina State University
- Catherine Juste
- INRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay
- Manuel Kleiner
- Department of Plant & Microbial Biology, North Carolina State University
- Olivier Langella
- Université Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE – Le Moulon
- Theresa Lehmann
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Emma Leith
- Department of Biochemistry Molecular Biology and Biophysics, University of Minnesota
- Patrick May
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Bart Mesuere
- VIB - UGent Center for Medical Biotechnology, VIB
- Guylaine Miotello
- Département Médicaments et Technologies pour la Santé (DMTS), Université Paris Saclay, CEA, INRAE, SPI
- Samantha L. Peters
- Biosciences Division, Oak Ridge National Laboratory
- Olivier Pible
- Département Médicaments et Technologies pour la Santé (DMTS), Université Paris Saclay, CEA, INRAE, SPI
- Pedro T. Queiros
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Udo Reichl
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Bernhard Y. Renard
- Bioinformatics Unit (MF1), Department for Methods Development and Research Infrastructure, Robert Koch Institute
- Henning Schiebenhoefer
- Bioinformatics Unit (MF1), Department for Methods Development and Research Infrastructure, Robert Koch Institute
- Alexander Sczyrba
- Faculty of Technology, Bielefeld University
- Alessandro Tanca
- Department of Biomedical Sciences, University of Sassari
- Kathrin Trappe
- Bioinformatics Unit (MF1), Department for Methods Development and Research Infrastructure, Robert Koch Institute
- Jean-Pierre Trezzi
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Sergio Uzzau
- Department of Biomedical Sciences, University of Sassari
- Pieter Verschaffelt
- VIB - UGent Center for Medical Biotechnology, VIB
- Martin von Bergen
- Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ GmbH
- Paul Wilmes
- Luxembourg Centre for Systems Biomedicine, University of Luxembourg
- Maximilian Wolf
- Bioprocess Engineering, Otto-von-Guericke University Magdeburg
- Lennart Martens
- VIB - UGent Center for Medical Biotechnology, VIB
- Thilo Muth
- Section eScience (S.3), Federal Institute for Materials Research and Testing
- DOI
- https://doi.org/10.1038/s41467-021-27542-8
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 15
Abstract
The authors present CAMPI, a large-scale multi-lab comparison of diverse metaproteomics workflows. CAMPI provides insights into the robustness of current methods, suggests further improvements to the field, and may pave the way for future community-driven metaproteomics projects.
