Chinese Medical Journal (May 2023)

Astragaloside in cancer chemoprevention and therapy

  • Yaning Wang,
  • Zhuo Zhang,
  • Zhaohua Cheng,
  • Wei Xie,
  • Hanjiao Qin,
  • Jiyao Sheng,
  • Yanjie Yin

DOI
https://doi.org/10.1097/CM9.0000000000002661
Journal volume & issue
Vol. 136, no. 10
pp. 1144 – 1154

Abstract

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Abstract. Tumor chemoprevention and treatment are two approaches aimed at improving the survival of patients with cancers. An ideal anti-tumor drug is that which not only kills tumor cells but also alleviates tumor-causing risk factors, such as precancerous lesions, and prevents tumor recurrence. Chinese herbal monomers are considered to be ideal treatment agents due to their multi-target effects. Astragaloside has been shown to possess tumor chemoprevention, direct anti-tumor, and chemotherapeutic drug sensitization effects. In this paper, we review the effects of astragaloside on tumor prevention and treatment and provide directions for further research.