Frontiers in Medicine (Jul 2022)
One Year Overview and Follow-Up in a Post-COVID Consultation of Critically Ill Patients
- Jessica González,
- Jessica González,
- Jessica González,
- Jessica González,
- María Zuil,
- María Zuil,
- María Zuil,
- María Zuil,
- Iván D. Benítez,
- Iván D. Benítez,
- Iván D. Benítez,
- David de Gonzalo-Calvo,
- David de Gonzalo-Calvo,
- David de Gonzalo-Calvo,
- María Aguilar,
- María Aguilar,
- Sally Santisteve,
- Sally Santisteve,
- Sally Santisteve,
- Sally Santisteve,
- Rafaela Vaca,
- Rafaela Vaca,
- Olga Minguez,
- Olga Minguez,
- Faty Seck,
- Faty Seck,
- Gerard Torres,
- Gerard Torres,
- Gerard Torres,
- Gerard Torres,
- Jordi de Batlle,
- Jordi de Batlle,
- Jordi de Batlle,
- Silvia Gómez,
- Silvia Gómez,
- Silvia Gómez,
- Silvia Gómez,
- Silvia Barril,
- Silvia Barril,
- Silvia Barril,
- Silvia Barril,
- Anna Moncusí-Moix,
- Anna Moncusí-Moix,
- Anna Moncusí-Moix,
- Aida Monge,
- Aida Monge,
- Aida Monge,
- Aida Monge,
- Clara Gort-Paniello,
- Clara Gort-Paniello,
- Clara Gort-Paniello,
- Ricard Ferrer,
- Ricard Ferrer,
- Adrián Ceccato,
- Laia Fernández,
- Laia Fernández,
- Ana Motos,
- Ana Motos,
- Jordi Riera,
- Jordi Riera,
- Rosario Menéndez,
- Rosario Menéndez,
- Darío Garcia-Gasulla,
- Oscar Peñuelas,
- Oscar Peñuelas,
- Gonzalo Labarca,
- Gonzalo Labarca,
- Jesús Caballero,
- Carme Barberà,
- Antoni Torres,
- Antoni Torres,
- Ferran Barbé,
- Ferran Barbé,
- Ferran Barbé,
- Ferran Barbé
Affiliations
- Jessica González
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Jessica González
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Jessica González
- Lleida Biomedical Research Institute, Lleida, Spain
- Jessica González
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- María Zuil
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- María Zuil
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- María Zuil
- Lleida Biomedical Research Institute, Lleida, Spain
- María Zuil
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Iván D. Benítez
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Iván D. Benítez
- Lleida Biomedical Research Institute, Lleida, Spain
- Iván D. Benítez
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- David de Gonzalo-Calvo
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- David de Gonzalo-Calvo
- Lleida Biomedical Research Institute, Lleida, Spain
- David de Gonzalo-Calvo
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- María Aguilar
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- María Aguilar
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Sally Santisteve
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Sally Santisteve
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Sally Santisteve
- Lleida Biomedical Research Institute, Lleida, Spain
- Sally Santisteve
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Rafaela Vaca
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Rafaela Vaca
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Olga Minguez
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Olga Minguez
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Faty Seck
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Faty Seck
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Gerard Torres
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Gerard Torres
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Gerard Torres
- Lleida Biomedical Research Institute, Lleida, Spain
- Gerard Torres
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Jordi de Batlle
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Jordi de Batlle
- Lleida Biomedical Research Institute, Lleida, Spain
- Jordi de Batlle
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Silvia Gómez
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Silvia Gómez
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Silvia Gómez
- Lleida Biomedical Research Institute, Lleida, Spain
- Silvia Gómez
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Silvia Barril
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Silvia Barril
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Silvia Barril
- Lleida Biomedical Research Institute, Lleida, Spain
- Silvia Barril
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Anna Moncusí-Moix
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Anna Moncusí-Moix
- Lleida Biomedical Research Institute, Lleida, Spain
- Anna Moncusí-Moix
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Aida Monge
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Aida Monge
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Aida Monge
- Lleida Biomedical Research Institute, Lleida, Spain
- Aida Monge
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Clara Gort-Paniello
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Clara Gort-Paniello
- Lleida Biomedical Research Institute, Lleida, Spain
- Clara Gort-Paniello
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Ricard Ferrer
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Ricard Ferrer
- Intensive Care Department, Vall d’Hebron Hospital Universitari, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Institut de Recerca, Barcelona, Spain
- Adrián Ceccato
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Laia Fernández
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Laia Fernández
- Department of Pulmonary, Hospital Clinic, Universitat de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
- Ana Motos
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Ana Motos
- Department of Pulmonary, Hospital Clinic, Universitat de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
- Jordi Riera
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Jordi Riera
- Intensive Care Department, Vall d’Hebron Hospital Universitari, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Institut de Recerca, Barcelona, Spain
- Rosario Menéndez
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Rosario Menéndez
- Department of Pulmonary, University and Polytechnic Hospital La Fe, Valencia, Spain
- Darío Garcia-Gasulla
- Barcelona Supercomputing Center, Barcelona, Spain
- Oscar Peñuelas
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Oscar Peñuelas
- Hospital Universitario de Getafe, Madrid, Spain
- Gonzalo Labarca
- 0Faculty of Medicine, University of Concepción, Concepción, Chile
- Gonzalo Labarca
- 1Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, Concepción, Chile
- Jesús Caballero
- 2Intensive Care Department, Hospital Universitari Arnau de Vilanova de Lleida, Lleida, Spain
- Carme Barberà
- 3Intensive Care Department, Hospital Universitari Santa Maria de Lleida, Lleida, Spain
- Antoni Torres
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- Antoni Torres
- Department of Pulmonary, Hospital Clinic, Universitat de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
- Ferran Barbé
- Department of Pulmonary, Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain
- Ferran Barbé
- Translational Research in Respiratory Medicine Group, Lleida, Spain
- Ferran Barbé
- Lleida Biomedical Research Institute, Lleida, Spain
- Ferran Barbé
- Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases, Institute of Health Carlos III, Madrid, Spain
- DOI
- https://doi.org/10.3389/fmed.2022.897990
- Journal volume & issue
-
Vol. 9
Abstract
The long-term clinical management and evolution of a cohort of critical COVID-19 survivors have not been described in detail. We report a prospective observational study of COVID-19 patients admitted to the ICU between March and August 2020. The follow-up in a post-COVID consultation comprised symptoms, pulmonary function tests, the 6-minute walking test (6MWT), and chest computed tomography (CT). Additionally, questionnaires to evaluate the prevalence of post-COVID-19 syndrome were administered at 1 year. A total of 181 patients were admitted to the ICU during the study period. They were middle-aged (median [IQR] of 61 [52;67]) and male (66.9%), with a median ICU stay of 9 (5–24.2) days. 20% died in the hospital, and 39 were not able to be included. A cohort of 105 patients initiated the follow-up. At 1 year, 32.2% persisted with respiratory alterations and needed to continue the follow-up. Ten percent still had moderate/severe lung diffusion (DLCO) involvement (<60%), and 53.7% had a fibrotic pattern on CT. Moreover, patients had a mean (SD) number of symptoms of 5.7 ± 4.6, and 61.3% met the criteria for post-COVID syndrome at 1 year. During the follow-up, 46 patients were discharged, and 16 were transferred to other consultations. Other conditions, such as emphysema (21.6%), COPD (8.2%), severe neurocognitive disorders (4.1%), and lung cancer (1%) were identified. A high use of health care resources is observed in the first year. In conclusion, one-third of critically ill COVID-19 patients need to continue follow-up beyond 1 year, due to abnormalities on DLCO, chest CT, or persistent symptoms.
Keywords