Data for microbe resistant engineered recombinant spider silk protein based 2D and 3D materials
Sushma Kumari,
Gregor Lang,
Elise DeSimone,
Christian Spengler,
Vanessa T. Trossmann,
Susanne Lücker,
Martina Hudel,
Karin Jacobs,
Norbert Krämer,
Thomas Scheibel
Affiliations
Sushma Kumari
Department of Biomaterials, Faculty of Engineering Science, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany
Gregor Lang
Department of Biomaterials, Faculty of Engineering Science, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany; Biopolymer Processing Group, Faculty of Engineering Science, University of Bayreuth, Ludwig-Thoma-Str. 36A, 95447 Bayreuth, Germany
Elise DeSimone
Department of Biomaterials, Faculty of Engineering Science, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany
Christian Spengler
Department of Experimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany
Vanessa T. Trossmann
Department of Biomaterials, Faculty of Engineering Science, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany
Susanne Lücker
Medical Center for Dentistry, Department of Paediatric Dentistry, Medical Center Gießen and Marburg, Justus-Liebig University Gießen, Schlagenzahl 14, 35392 Gießen, Germany
Martina Hudel
Institute of Medical Microbiology, Justus-Liebig University Gießen, Schubertstraße 81, 35392 Gießen, Germany
Karin Jacobs
Department of Experimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany
Norbert Krämer
Medical Center for Dentistry, Department of Paediatric Dentistry, Medical Center Gießen and Marburg, Justus-Liebig University Gießen, Schlagenzahl 14, 35392 Gießen, Germany
Thomas Scheibel
Department of Biomaterials, Faculty of Engineering Science, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany; Bayreuth Center for Material Science and Engineering (BayMAT), Germany; Bavarian Polymer Institute (BPI), Germany; Bayreuth Center for Colloids and Interfaces (BZKG), Germany; Bayreuth Center for Molecular Biosciences (BZMB), University of Bayreuth, Universitätsstraße 30, 95447 Bayreuth, Germany; Corresponding author.
Data presented in this article describe bacterial and fungal repellent properties of 2D-films and 3D-hydrogels made of different recombinantly produced spider silk proteins based on consensus sequences of Araneus diadematus dragline silk proteins (fibroin 3 and 4). Here, the attachment, growth, and microbial colonization of Streptococcus mutans (S. mutans) as well as Candida albicans (C. albicans) on plane and micro-patterned films were visualized by scanning electron microscopy (SEM). Also, microbial viability data are provided of Escherichia coli (E. coli) and Pichia pastoris (P. pastoris) on hydrogels made of eADF4(C16) and eADF4(C16)-RGD, quantified using the Alamar blue assay. Experimental results, design of a post-operative contamination model of microbes with mammalian cells, and methods in the data article refer to the research paper “Engineered spider silk-based 2D and 3D materials prevent microbial infestation” published recently [1].
