Nature Communications (Sep 2017)

Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

  • Katerina Naydenova,
  • Christopher J. Russo

DOI
https://doi.org/10.1038/s41467-017-00782-3
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 5

Abstract

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A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.