Effectiveness of Pyridoxine and Pyridostigmine in the Treatment of Vincristine-Induced Bilateral Ptosis and External Ophthalmoplegia: A Case Report

Osman Okan Olcaysu; Ahmet Altun; Elif Olcaysu; Sertaç Argun Kıvanç; Zuhal Keskin Yıldırım

doi:10.4274/tjo.62533

Türk Oftalmoloji Dergisi (Aug 2014)

Effectiveness of Pyridoxine and Pyridostigmine in the Treatment of Vincristine-Induced Bilateral Ptosis and External Ophthalmoplegia: A Case Report

Osman Okan Olcaysu,
Ahmet Altun,
Elif Olcaysu,
Sertaç Argun Kıvanç,
Zuhal Keskin Yıldırım

Affiliations

Osman Okan Olcaysu: Erzurum Region Education and Research Hospital, Clinic of Ophthalmology, Erzurum, Turkey
Ahmet Altun: Fatih Sultan Mehmet Education and Research Hospital, Clinic of Ophthalmology, İstanbul, Turkey
Elif Olcaysu: Uludağ University Faculty of Medicine, Department of Ophthalmology, Bursa Turkey
Sertaç Argun Kıvanç: Fatih Sultan Mehmet Education and Research Hospital, Clinic of Ophthalmology, İstanbul, Turkey
Zuhal Keskin Yıldırım: Atatürk University Faculty of Medicine, Department of Pediatrics, Erzurum, Turkey

DOI: https://doi.org/10.4274/tjo.62533
Journal volume & issue: Vol. 44, no. 4
pp. 330 – 331

Abstract

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In this manuscript, we present the case of a patient with acute lymphoblastic leukemia who developed vincristine-induced bilateral ptosis and external ophthalmoplegia and who was treated successfully with pyridoxine and pyridostigmine. Pyridostigmine and pyridoxine are promising treatment option in cases of vincristine-induced neuropathy. (Turk J Ophthalmol 2014; 44: 330-1)

Published in Türk Oftalmoloji Dergisi

ISSN: 1300-0659 (Print); 2147-2661 (Online)
Publisher: Galenos Yayinevi
Country of publisher: Türkiye
LCC subjects: Medicine: Ophthalmology
Website: http://www.oftalmoloji.org/home

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