Nature Communications (Jan 2021)

Spread spectrum SERS allows label-free detection of attomolar neurotransmitters

  • Wonkyoung Lee,
  • Byoung-Hoon Kang,
  • Hyunwoo Yang,
  • Moonseong Park,
  • Ji Hyun Kwak,
  • Taerin Chung,
  • Yong Jeong,
  • Bong Kyu Kim,
  • Ki-Hun Jeong

DOI
https://doi.org/10.1038/s41467-020-20413-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Identification of neurotransmitters remains challenging for surface enhanced Raman spectroscopy (SERS) due to presence of noise. Here, the authors present spread spectrum SERS, which by encoding excited light and decoding SERS signals enables detection of unlabelled neurotransmitters at attomolar concentrations.