MORPHOLOGY AND DISTRIBUTION OF Α-NAPHTHYL BUTIRATE ESTERASE AND NAPHTHOL AS-D CHLOROACETATE ESTERASE IN NORMAL MYELOMONOCYTIC PRECURSORS STUDIED BY THE CELL MICROARRAY

Abstract

Here we describe and qualitatively characterize the distribution of mononuclear cells isolated from bone marrow aspirate of healthy donors and sorted by their surface CD antigens on a cell microarray by morphology (for 11 donors) and by absence or presence of α-naphthyl butyrate esterase and naphthol AS-D chloroacetate esterase (for 9 donors). These data can be used as a reference for the diagnosis of acute myeloid leukemia using the cell microarray.

Keywords

• cell microarray
• normal bone marrow
• myeloid lineages
• α-naphthyl butyrate esterase
• naphthol as-d chloroacetate esterase