Mirror of Research in Veterinary Sciences and Animals (Jul 2016)
The effect of milk of the camel on some blood and liver parameters in formaldehyde induced arthritis in rats
Abstract
This study was designed to evaluate the effects of camel's milk on some blood and liver parameters of formaldehyde induced arthritis rats. Forty-two adult male rats were used in two experiments. The preliminary study was done to induce arthritis and to evaluate the changing in blood and liver enzyme parameters. Twelve adult male rats were divide into two groups. All animals in group 1( G1/ control) and group ( G2) were injected at the Plantar fascia of the left foot with 0.1 ml physiological saline and 0.1 ml formaldehyde twice ( 1st and 3rd day of the experiment) respectively. The experiment study was done to evaluate the anti-arthritic nature of camel's milk against the formaldehyde induced arthritis in rats and its effect on some blood and liver parameters. This experiment included 30 adult male rats and divided into five groups (G3, G4, G5, G6, and G7) each with 6 rats and received different treatment according to the design of the experiment that explained in the methods. The results of this study revealed significant elevation (p< 0.05) in the Leukocyte Count (WBC) especially in the neutrophil and monocyte and in the level of (AST, ALT, ALP). There were also significant decrease (p< 0.05) in the percentage of lymphocytes and monocyte in formaldehyde induced arthritis rats, when compare with the control group. The treated groups G6 in the second experiment revealed significant decrease (p< 0.05) in the in the WBC especially in the neutrophil and monocyte and in the level of (AST, ALT, ALP). Moreover, there was significant elevation (P< 0.05) in the percentage of lymphocyte. In conclusion, the results of this study revealed anti- arthritic activity of camel's milk against the formaldehyde induced arthritis in rats.
