Journal of Education, Health and Sport (Aug 2022)

Multiple myeloma and kidney disease

  • Natalia Zarankiewicz,
  • Katarzyna Kosz,
  • Martyna Zielińska,
  • Klaudia Remjasz,
  • Aleksandra Kuchnicka,
  • Julia Kuchnicka,
  • Klaudia Sapuła,
  • Jakub Aleksandrowicz,
  • Wojciech Siedlecki

DOI
https://doi.org/10.12775/JEHS.2022.12.08.089
Journal volume & issue
Vol. 12, no. 8

Abstract

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Abstract Background: Multiple myeloma is a clonal plasma cell neoplasm which affects 1% of all malignancies. In this article we reviewed epidemiology, symptoms with particular attention to renal failure and its manifestation in multiple myeloma (MM). Material and methods: This paper was based on medical articles collected in PubMed from 2001 to 2022, medical websites and books. The research has been done by looking through key words such as: „multiple myeloma”, „myeloma cast nephropathy”, „bortezomib”, „RANKL” Results: Multiple myeloma has indolent course and many patients present renal disorders at the moment of diagnosis. The use of novel therapies can reverse renal failure. Conclusions: Treatment of the patients with MM and kidney disease is challenging for health care professionals. Doctors have to adjust treatment to provide the best therapeutic effects.

Keywords