Generation of a human Tropomyosin 1 knockout iPSC line

Madison B. Wilken; Jean Ann Maguire; Lea V. Dungan; Alyssa Gagne; Catherine Osorio-Quintero; Elisa A Waxman; Stella T. Chou; Paul Gadue; Deborah L. French; Christopher S. Thom

Stem Cell Research (Sep 2023)

Generation of a human Tropomyosin 1 knockout iPSC line

Madison B. Wilken,
Jean Ann Maguire,
Lea V. Dungan,
Alyssa Gagne,
Catherine Osorio-Quintero,
Elisa A Waxman,
Stella T. Chou,
Paul Gadue,
Deborah L. French,
Christopher S. Thom

Affiliations

Madison B. Wilken: Division of Neonatology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Jean Ann Maguire: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Lea V. Dungan: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Alyssa Gagne: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Catherine Osorio-Quintero: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Elisa A Waxman: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Stella T. Chou: Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Division of Hematology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Paul Gadue: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Deborah L. French: Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Christopher S. Thom: Division of Neonatology, Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Corresponding author at: Children’s Hospital of Philadelphia, 10-052 Colket Translational Research Building, 3501 Civic Center Blvd., Philadelphia, PA 19104, USA.

Journal volume & issue: Vol. 71
p. 103161

Abstract

Read online

The CHOPWT17_TPM1KOc28 iPSC line was generated to interrogate the functions of Tropomyosin 1 (TPM1) in primary human cell development. This line was reprogrammed from a previously published wild type control iPSC line.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

About the journal