Journal of Veterinary Research (Jan 2020)
Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
Abstract
Marek’s disease virus (MDV) can cause malignant T-cell lymphomas and immunosuppression in chickens. Macrophage migration inhibitory factor (MIF) not only plays a critical role in inhibiting T-cell responses, but also contributes to multiple aspects of tumour progression. The aim of this study was to reveal the potential role of MIF in the pathogenesis of MDV infection.
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