PLoS ONE (Jan 2020)

Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis.

  • Manuela Savino,
  • Anna Casula,
  • Shalini Santhakumaran,
  • David Pitcher,
  • Esther Wong,
  • Winnie Magadi,
  • Katharine M Evans,
  • Fran Benoy-Deeney,
  • James Griffin,
  • Lucy Plumb,
  • Retha Steenkamp,
  • Dorothea Nitsch,
  • James Medcalf

DOI
https://doi.org/10.1371/journal.pone.0241263
Journal volume & issue
Vol. 15, no. 10
p. e0241263

Abstract

Read online

Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1-88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94-1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group.