Journal of Pharmacy and Bioallied Sciences (Jan 2024)

Periapical healing outcome of endodontic re-treatment using calcium silicates versus resin-based sealers: A systematic review

  • Izaz Shaik,
  • Manisha Kusuma,
  • Mennattallah Elsayed,
  • Keerthini Veluru,
  • Aeliya Nabeel,
  • Ravi Sindhura

DOI
https://doi.org/10.4103/jpbs.jpbs_556_23
Journal volume & issue
Vol. 16, no. 5
pp. 90 – 92

Abstract

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Aim: This systematic review was conducted with the purpose of analyzing the effects of root-end sealers in endodontic re-treatment cases and comparing calcium-based sealers with sealers, which were resin-based. Methodology: We conducted this review based on the principles of Cochrane systematic type of studies and also based on guidelines of Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA). An exhaustive search was conducted across PubMed, Medline, and Embase databases for the studies, which were based on root end sealers in cases of endodontic re-treatments. The data were then analyzed statistically with the help of SPSS 25.0. Results: It was seen that when comparing pain levels in post-obturation cases with these sealers after 24 hours and 48 hours, not much of statistically noteworthy differences were evident. Mean difference (MD) values at 24 hours were -0.20 with confidence intervals between -0.44 and 0.07 and P value of 0.15, whereas in case of 48 hours, MD was -0.36, CI- 0.65, and P value was 0.03. However, the results were slightly better with calcium-based sealers. Conclusion: Calcium silicate-based root end obturation sealers had similar performance when compared to resin-based sealers when we compared variables like pain intensity, etc.

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