Dynamics of glutathione system indices in patients with non-removable orthopedic prostheses

Abstract

The level of thiol SH-groups and the activity of glutathione reductase in the oral fluid of patients with nonremovable ceramic and cermet structures have been determined. 57 patients with cermet and ceramic non-removable bridges were examined. The average age of the patients was 36.3 ± 3.55 years. The study included patients who did not have more than 3 teeth. A total of 137 non-removable bridges were found, of which 61 were ceramic-metal and 76 ceramics were whole-ceramic. The patients were divided into two groups: group I - 25 patients with cermet removable bridge restorations; Group II - 32 patients with whole-ceramic restorations. After 6 months. after prosthetics in comparison with the initial, the concentration of thiol groups in patients with cermet prosthesis increased by 21.1%, in patients with ceramic prostheses - by 27.2% (p <0.05). After 6 months. the activity of the enzyme in patients of the I group was higher than the initial activity by 27.4% (p <0.05) and above the activity, which was observed after 7 days, by 21.6%. At this stage of the study, the GR activity was below the control one by 7.8%. In patients of group II after 6 months. after prosthetics, the enzyme activity was higher than the baseline by 45.6% (p <0.05) and 26.4% (p <0.05) higher than 7 days later. In patients with ceramic restorations, GR activity after 6 months. practically did not differ from the control one.

Keywords

• ротовая жидкость
• протезирование
• несъемные металлокерамические
• керамические протезы
• тиоловые группы
• глутатионредуктаза