Communications Biology (Nov 2021)

Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis

  • Xiuxing Liu,
  • Binyao Chen,
  • Zhaohao Huang,
  • Runping Duan,
  • He Li,
  • Lihui Xie,
  • Rong Wang,
  • Zhaohuai Li,
  • Yuehan Gao,
  • Yingfeng Zheng,
  • Wenru Su

DOI
https://doi.org/10.1038/s42003-021-02859-8
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 15

Abstract

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Liu et al. use mass cytometry and single-cell RNA sequencing of healthy human blood samples to obtain a comprehensive human immune cell landscape when sleep duration is reduced. Their findings could provide highdimensional insight into the cellular and molecular mechanisms of pathologic conditions affect by poor sleep.