Trends in pediatric community-onset Staphylococcus aureus antibiotic susceptibilities over a five-year period in a multihospital health system

Erica C. Prochaska; Shaoming Xiao; Pranita D. Tamma; Anna Sick-Samuels; Christina Schumacher; Avinash Gadala; Karen C. Carroll; Aaron M. Milstone

doi:10.1017/ash.2022.370

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2023)

Trends in pediatric community-onset Staphylococcus aureus antibiotic susceptibilities over a five-year period in a multihospital health system

Erica C. Prochaska,
Shaoming Xiao,
Pranita D. Tamma,
Anna Sick-Samuels,
Christina Schumacher,
Avinash Gadala,
Karen C. Carroll,
Aaron M. Milstone

Affiliations

Erica C. Prochaska: ORCiD; Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Shaoming Xiao: Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Pranita D. Tamma: Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Anna Sick-Samuels: ORCiD; Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Hospital Epidemiology and Infection Control, Johns Hopkins Health System, Baltimore, Maryland
Christina Schumacher: Division of General Pediatrics, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Avinash Gadala: ORCiD; Department of Hospital Epidemiology and Infection Control, Johns Hopkins Health System, Baltimore, Maryland
Karen C. Carroll: ORCiD; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland
Aaron M. Milstone: ORCiD; Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Hospital Epidemiology and Infection Control, Johns Hopkins Health System, Baltimore, Maryland

DOI: https://doi.org/10.1017/ash.2022.370
Journal volume & issue: Vol. 3

Abstract

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The epidemiology of community-onset Staphylococcus aureus infections is evolving. We performed a multihospital, retrospective study of pediatric community-onset S. aureus susceptibilities between 2015 and 2020. Oxacillin and clindamycin susceptibility remained lower at 67% and 75%, respectively. Tetracycline and trimethoprim-sulfamethoxazole susceptibility remained high at >90%. Oxacillin susceptibility was highest in invasive infections.

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

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