Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies

• Rabia Mehmood,
• Amina Sadiq,
• Reem I. Alsantali,
• Ehsan Ullah Mughal,
• Meshari A. Alsharif,
• Nafeesa Naeem,
• Asif Javid,
• Munirah M. Al-Rooqi,
• Gul-e-Saba Chaudhry,
• Saleh A. Ahmed

Affiliations

Rabia Mehmood

Department of Chemistry, Govt. College Women University, Sialkot, Pakistan

Amina Sadiq

Department of Chemistry, Govt. College Women University, Sialkot, Pakistan

Reem I. Alsantali

Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia

Ehsan Ullah Mughal

Department of Chemistry, University of Gujrat, Gujrat, Pakistan

Meshari A. Alsharif

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia

Nafeesa Naeem

Department of Chemistry, University of Gujrat, Gujrat, Pakistan

Asif Javid

Department of Chemistry, University of Gujrat, Gujrat, Pakistan

Munirah M. Al-Rooqi

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia

Gul-e-Saba Chaudhry

Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia

Saleh A. Ahmed

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia