Nature Communications (Mar 2021)

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

  • Dashuai Zhu,
  • Zhenhua Li,
  • Ke Huang,
  • Thomas G. Caranasos,
  • Joseph S. Rossi,
  • Ke Cheng

DOI
https://doi.org/10.1038/s41467-021-21682-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Current routes to deliver therapeutics to the heart are normally invasive or difficult to perform. Here the authors develop intrapericardial injection as an efficient, easy-to-perform and minimally invasive method to deliver therapeutics for cardiac repair.