A Novel
<i>Toxoplasma</i>
Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery
Jessica H. Chern,
Rebecca R. Pasquarelli,
Andy S. Moon,
Allan L. Chen,
Jihui Sha,
James A. Wohlschlegel,
Peter J. Bradley
Affiliations
Jessica H. Chern
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Rebecca R. Pasquarelli
Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA
Andy S. Moon
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Allan L. Chen
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Jihui Sha
Department of Biological Chemistry and Institute of Genomics and Proteomics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
James A. Wohlschlegel
Department of Biological Chemistry and Institute of Genomics and Proteomics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
The inner membrane complex (IMC) is a peripheral membrane and cytoskeletal system that is organized into intriguing rectangular plates at the periphery of the parasite. The IMC plates are delimited by an array of IMC suture proteins that are tethered to both the membrane and the cytoskeleton and are thought to provide structure to the organelle.
