Non- Mydriatic Fundus Photograph Diabetic Retinopathy Screening in Primary Care Unit Setting by Paramedic Personnel

Abstract

Objective: To study the accuracy and agreement of non-mydriatic fundus photographic screening of diabetic retinopathy (DR) by well-trained paramedic personnel compared to retinal specialists and to obtain the prevalence of DR stages in primary care unit (PCU). Methods: The non-mydriatic fundus photographs of diabetic patients taken at PCU were retrospectively reviewed and graded into three groups; no DR, non-proliferative DR (NPDR), proliferative DR (PDR) by two independent well-trained nurses compared to retinal specialists between November, 2015 to March, 2016. The results were statistically analyzed to determine the level of agreement between the nurses and the retinal specialists. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of each nurse were also calculated. Results: Fundus photographs of 475 patients were obtained. The patients included 129 (27.2%) males and 346 (72.8%) females with the age of 59.94 ± 8.62 years. The agreements between two readers and the retinal specialists were moderate (κ =0.46 and 0.54). The sensitivity and specificity of the first reader were 71.69% and 87.91% and the second reader were 75.50% and 90.8%, respectively. The PPV and NPV were 42.69% and 98.11% for the first reader and 50.60% and 96.70% for the second. The overall accuracy of the first nurse was 86.1% while the second was 96.0%. The prevalence of any stages of DR was 11.1%, NPDR 10.5% and PDR 0.6%. Conclusion: The single field non-mydriatic fundus photography read by trained paramedic personnel is one of the effective preliminary screening modalities. However, the continuous evaluation of the capabilities of the readers should be performed so that the patients with any stages of DR would be appropriately referred to ophthalmologists. This strategy would lead to the significant improvement of the DR screening in the country with high burden of diabetic patients.

Keywords

• Diabetic retinopathy screening; fundus camera; single-filed fundus photographs; paramedic personnel (Siriraj Med J 2017;69: 122-127)