BMC Cancer (Nov 2024)
Dosimetric effects of prone immobilization devices on skin in intensity-modulated radiation therapy for gynecologic cancer: a retrospective study
Abstract
Abstract Objective The dose perturbation effect of immobilization devices is often overlooked in intensity-modulated radiation therapy (IMRT) for gynecologic cancer. This retrospective study assessed the dosimetric effects of a prone immobilization device combined with a belly board (PIDBB) on the skin. Methods We recruited 63 women with gynecologic cancer undergoing postoperative IMRT at our institute. A 0.3 cm thick skin contour and body contours with or without PIDBB system were outlined for each patient. Dose calculations were performed for the two sets of contours using the same plan, named Plan− and Plan+, respectively. The accuracy of calculated doses was verified by gafchromic EBT3 film and anthropomorphic phantom. Results The V 40 Gy, V 30 Gy, V 20 Gy, V 15 Gy and D mean of skin increased by 56.94%, 65.48%, 53.12%, 41.91%, and 1.91%, respectively. Even after excluding the effect of prescription dose coverage, the V 40 Gy, V 30 Gy, V 20 Gy, V 15 Gy and D mean of skin still increased by 46.90%, 92.07%, 72.81%, 52.25%, and 18.06%, respectively. No significant differences were observed in doses to other organs at risk. The EBT3 measurements showed that the skin dose map to the anthropomorphic phantom was 23.79% higher than that calculated by the treatment planning system without the PIDBB system. Conclusions While the PIDBB system effectively reduces the low dose to small intestine, it also induces radiation attenuation, leading to a sharp increase in skin dose, particularly in patients receiving radiation in the groin and perineum area. Therefore, immobilization devices should be included in the external contour to account for dose attenuation and the increment in skin dose. Trial registration This study does not report on interventions in human health care.
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