Advanced Electrodegradation of Doxorubicin in Water Using a 3-D Ti/SnO₂ Anode

Abstract

This study investigated the application of an advanced electrooxidation process with three-dimensional tin oxide deposited onto a titanium plate anode, named 3-D Ti/SnO2, for the degradation and mineralization of one of the most important emerging contaminants with cytostatic properties, doxorubicin (DOX). The anode was synthesized using a commercial Ti plate, with corrosion control in acidic medium, used as a substrate for SnO2 deposition by the spin-coating method. X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses revealed that porous SnO2 was obtained, and the rutile phase of TiO2 was identified as an intermediary substrate onto the Ti plate. The results of CV analysis allowed us to determine the optimal operating conditions for the electrooxidation process conducted under a constant potential regime, controlled by the electron transfer or the diffusion mechanisms, involving hydroxyl radicals. The determination of UV–VIS spectra, total organic carbon (TOC), and chemical oxygen demand (COD) allowed us to identify the degradation mechanism and pathway of DOX onto the 3-D Ti/SnO2 anode. The effective degradation and mineralization of DOX contained in water by the electrooxidation process with this new 3-D dimensionally stable anode (DSA) was demonstrated in this study.

Keywords

• doxorubicin
• emerging pollutants in water
• advanced water treatment
• advanced electrooxidation
• porous dimensionally stable anode (DSA)
• Ti/SnO₂