Clinical Outcomes and Factors Affecting the Outcome of Decompressive Craniectomy: Analysis of 50 Cases

Abstract

Objective: Decompressive craniectomy (DC) is used as the last-stage method in the treatment of increased intracranial pressure (ICP). However, clinical outcomes reported in the literature are contradictory.Methods: Medical records were retrospectively reviewed for 50 increased ICP cases that had been diagnosed and undergone DC at our hospital between February 2011 and February 2017. The patients’ characteristics such as age, sex, presence of comorbidities, pre- and postoperative Glasgow Coma Scale (GCS) scores, blood pressure, hemoglobin values, radiological findings, DC time, width of craniectomy, length of stay in the intensive care unit (ICU), and Glasgow Outcome Scale (GOS) were recorded. According to their outcome, the patients were divided into two groups with good (GOS = 4-5) and poor (GOS = 1-3) prognosis, respectively, according to their last examination. It was evaluated whether these parameters showed significant differences between the groups and between the deceased patients and survivors.Results: A total of 50 patients (35 male and 15 female) had been treated with DC. The mean age was 40.5±22.2 years. Head trauma was the etiology of increased ICP in 68% of the cases (n=34). The median of preoperative GCS was 6 (range: 3-15), and the mean midline shift on admission was 10.3±5.1 mm. Seventy-two percent of the cases (n=36) were treated with DC on the day of admission from the emergency department. The median of postoperative GCS was 7 (range: 3-15). The patients were followed up for a mean of 24.4 days in the ICU, and 30 patients were lost after a mean of 24.6 days. The survivors were followed up for a mean of 7.4±12.5 months. Factors affecting survival periods were age of the patient, short edge length of the DC (not long edge) and early postoperative GCS score after the DC. The comparison between survivors and deceased patients showed that the mean age of survivors was significantly lower than that of deceased patients (p=0.047). Postoperative GCS scores after DC were significantly lower in the patients who had died (p=0.0001).Conclusion: Age, short edge length of the craniectomy and postoperative neurological status are factors affecting surgical outcomes. These factors can play a role in selecting patient candidates who have to receive DC.

Keywords

• decompressive craniectomy
• increased intracranial pressure
• craniectomy
• outcome