Clinical Infection in Practice (Jul 2022)

Aspergillus wound infection in an immune-competent patient – A case report

  • Elchanan Quint,
  • Ivan Kukeev,
  • Hannah Glinter,
  • Anton Osyntsov,
  • Guy Barsky,
  • Alex Vakhrushev,
  • Evgeni Brotfain,
  • Daniel Grupel

Journal volume & issue
Vol. 15
p. 100146

Abstract

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Background: Abdominal aspergillosis is a life-threatening, opportunistic fungal infection that mainly affects immunocompromised patients. In this report, we present a case of abdominal surgical site aspergillosis in an immunocompetent patient. Case presentation: A 74-year-old immune-competent woman that had a prolonged hospitalization in the Intensive Care (ICU) Unit with several abdominal surgeries and multiple antibiotic treatment regimens. The abdomen remained open between interventions. 21 days following ICU admission a diagnosis of surgical site aspergillosis was made, treated with systemic and topical antifungal treatment. Conclusions: While nosocomial aspergillosis typically affects immunocompromised patients, immunocompetent patients also become susceptible when the skin barrier is broken and tissue is exposed to the environment. Treatment consisted with surgical debridement and systemic antifungal therapy. This case provides an example of extensive and rare surgical infection.

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