Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients

• Susan Dutton,
• Ines Rombach,
• Joanna Black,
• Paul Harden,
• Giovanna Lombardi,
• William Petchey,
• Kathryn Wood,
• Fadi Issa,
• Matthew Oliver Brook,
• Joanna Hester,
• Matthew James Bottomley,
• Seetha Abdul-Wahab,
• Andrew Bushell,
• Peter Friend

Affiliations

Susan Dutton

senior medical statistician

Ines Rombach

medical statistician

Joanna Black

1 School of Optometry & Vision Science, The University of Auckland Faculty of Medical and Health Sciences, Auckland, New Zealand

Paul Harden

Oxford Transplant Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Giovanna Lombardi

1Medical Research Council Centre for Transplantation, King`s College London, London, UK

William Petchey

Cardiology, West Suffolk Hospitals NHS Trust, Bury Saint Edmunds, Suffolk, UK

Kathryn Wood

Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa

Fadi Issa

Transplantation Research Immunology Group, University of Oxford Nuffield Department of Surgical Sciences, Oxford, UK

Matthew Oliver Brook

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK

Joanna Hester

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK

Matthew James Bottomley

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK

Seetha Abdul-Wahab

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK

Andrew Bushell

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK

Peter Friend

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK