Nature Communications (Nov 2022)
Impact of pulmonary African trypanosomes on the immunology and function of the lung
- Dorien Mabille,
- Laura Dirkx,
- Sofie Thys,
- Marjorie Vermeersch,
- Daniel Montenye,
- Matthias Govaerts,
- Sarah Hendrickx,
- Peter Takac,
- Johan Van Weyenbergh,
- Isabel Pintelon,
- Peter Delputte,
- Louis Maes,
- David Pérez-Morga,
- Jean-Pierre Timmermans,
- Guy Caljon
Affiliations
- Dorien Mabille
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- Laura Dirkx
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- Sofie Thys
- Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp
- Marjorie Vermeersch
- Center for Microscopy and Molecular Imaging, Université libre de Bruxelles
- Daniel Montenye
- Center for Microscopy and Molecular Imaging, Université libre de Bruxelles
- Matthias Govaerts
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- Sarah Hendrickx
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- Peter Takac
- Institute of Zoology, Slovak Academy of Sciences
- Johan Van Weyenbergh
- Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute of Medical Research, KU Leuven
- Isabel Pintelon
- Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp
- Peter Delputte
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- Louis Maes
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- David Pérez-Morga
- Center for Microscopy and Molecular Imaging, Université libre de Bruxelles
- Jean-Pierre Timmermans
- Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp
- Guy Caljon
- Laboratory of Microbiology, Parasitology and Hygiene, Infla-Med Centre of Excellence, University of Antwerp
- DOI
- https://doi.org/10.1038/s41467-022-34757-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 18
Abstract
A number of human African trypanosomiasis, or sleeping sickness, patients suffer from respiratory symptoms commonly attributed to cardiac insufficiency. Here, the authors characterise the role of pulmonary Trypanosoma brucei in respiratory infection.