Nature Communications (Nov 2022)

Impact of pulmonary African trypanosomes on the immunology and function of the lung

  • Dorien Mabille,
  • Laura Dirkx,
  • Sofie Thys,
  • Marjorie Vermeersch,
  • Daniel Montenye,
  • Matthias Govaerts,
  • Sarah Hendrickx,
  • Peter Takac,
  • Johan Van Weyenbergh,
  • Isabel Pintelon,
  • Peter Delputte,
  • Louis Maes,
  • David Pérez-Morga,
  • Jean-Pierre Timmermans,
  • Guy Caljon

DOI
https://doi.org/10.1038/s41467-022-34757-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 18

Abstract

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A number of human African trypanosomiasis, or sleeping sickness, patients suffer from respiratory symptoms commonly attributed to cardiac insufficiency. Here, the authors characterise the role of pulmonary Trypanosoma brucei in respiratory infection.