Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

Jane S. Huang; Tenzin Kunkhyen; Alexander N. Rangel; Taryn R. Brechbill; Jordan D. Gregory; Emily D. Winson-Bushby; Beichen Liu; Jonathan T. Avon; Ryan J. Muggleton; Claire E. J. Cheetham

doi:10.1038/s41467-022-33967-6

Nature Communications (Oct 2022)

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

Jane S. Huang,
Tenzin Kunkhyen,
Alexander N. Rangel,
Taryn R. Brechbill,
Jordan D. Gregory,
Emily D. Winson-Bushby,
Beichen Liu,
Jonathan T. Avon,
Ryan J. Muggleton,
Claire E. J. Cheetham

Affiliations

Jane S. Huang: Department of Neurobiology, University of Pittsburgh
Tenzin Kunkhyen: Department of Neurobiology, University of Pittsburgh
Alexander N. Rangel: Department of Neurobiology, University of Pittsburgh
Taryn R. Brechbill: Department of Neurobiology, University of Pittsburgh
Jordan D. Gregory: Department of Neurobiology, University of Pittsburgh
Emily D. Winson-Bushby: Department of Neurobiology, University of Pittsburgh
Beichen Liu: Department of Neurobiology, University of Pittsburgh
Jonathan T. Avon: Department of Neurobiology, University of Pittsburgh
Ryan J. Muggleton: Department of Neurobiology, University of Pittsburgh
Claire E. J. Cheetham: Department of Neurobiology, University of Pittsburgh

DOI: https://doi.org/10.1038/s41467-022-33967-6
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 19

Abstract

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New olfactory sensory neurons (OSNs) wire into highly organized olfactory bulb circuits throughout life. Here, the authors show that immature OSNs provide behaviourally relevant sensory input to olfactory bulb neurons that is functionally distinct from that provided by mature OSNs.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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