PEComa with Transcription Factor E3 Overexpression: A Diagnostic and Therapeutic Challenge

Abstract

PEComa with transcription factor E3 overexpression, most commonly through gene rearrangement, represents a biologically distinct subset of disease. We present here an illustrative case to highlight its diagnostic and therapeutic challenge in the context of potential pathogenic signaling pathways.

Keywords

• PEComa
• Transcription factor E3
• Gene rearrangement