The role of polymorphisms in glutathione-related genes in asbestos-related diseases

Franko Alenka; Goricar Katja; Dodic Fikfak Metoda; Kovac Viljem; Dolzan Vita

doi:10.2478/raon-2021-0002

Radiology and Oncology (Jan 2021)

The role of polymorphisms in glutathione-related genes in asbestos-related diseases

Franko Alenka,
Goricar Katja,
Dodic Fikfak Metoda,
Kovac Viljem,
Dolzan Vita

Affiliations

Franko Alenka: Clinical Institute of Occupational Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Goricar Katja: Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Dodic Fikfak Metoda: Clinical Institute of Occupational Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Kovac Viljem: Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Dolzan Vita: Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2021-0002
Journal volume & issue: Vol. 55, no. 2
pp. 179 – 186

Abstract

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The study investigated the influence of GCLC, GCLM, GSTM1, GSTT1 and GSTP1 polymorphisms, as well as the influence of interactions between polymorphism and interactions between polymorphisms and asbestos exposure, on the risk of developing pleural plaques, asbestosis and malignant mesothelioma (MM).

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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Abstract

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