Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity
Simona Rubino,
Rosa Alduina,
Patrizia Cancemi,
Maria Assunta Girasolo,
Vita Di Stefano,
Santino Orecchio,
Silvestre Buscemi,
Ivana Pibiri
Affiliations
Simona Rubino
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Rosa Alduina
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Patrizia Cancemi
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Maria Assunta Girasolo
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Vita Di Stefano
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Santino Orecchio
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Silvestre Buscemi
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Ivana Pibiri
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Parco d’Orleans II, Viale delle Scienze-Bd. 16-17, 90128 Palermo, Italy
Two mononuclear Pd(II) complexes [PdCl2(pfptp)] (1) and [PdCl2(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains.
