Assessing Inflammatory Bowel Disease-Associated Antibodies in Caucasian and First Nations Cohorts

Charles N Bernstein; Hani El-Gabalawy; Michael Sargent; Carol J Landers; Patricia Rawsthorne; Brenda Elias; Stephan R Targan

doi:10.1155/2011/712350

Canadian Journal of Gastroenterology (Jan 2011)

Assessing Inflammatory Bowel Disease-Associated Antibodies in Caucasian and First Nations Cohorts

Charles N Bernstein,
Hani El-Gabalawy,
Michael Sargent,
Carol J Landers,
Patricia Rawsthorne,
Brenda Elias,
Stephan R Targan

Affiliations

Charles N Bernstein: IBD Clinical & Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada
Hani El-Gabalawy: Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Michael Sargent: IBD Clinical & Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada
Carol J Landers: Cedars Sinai Medical Center, Los Angeles, California, USA
Patricia Rawsthorne: IBD Clinical & Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada
Brenda Elias: Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
Stephan R Targan: Cedars Sinai Medical Center, Los Angeles, California, USA

DOI: https://doi.org/10.1155/2011/712350
Journal volume & issue: Vol. 25, no. 5
pp. 269 – 273

Abstract

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BACKGROUND: First Nation populations in Canada have a very low incidence of inflammatory bowel disease (IBD). Based on typical infections in this population, it is plausible that the First Nations react differently to microbial antigens with a different antibody response pattern, which may shed some light as to why they experience a low rate of IBD.

Published in Canadian Journal of Gastroenterology

ISSN: 0835-7900 (Print); 1916-7237 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the digestive system. Gastroenterology
Website: https://www.hindawi.com/journals/cjgh/

About the journal