Monocyte chemoattractant protein-1 in patients with peripheral arterial disease

Abstract

Background: Chemokine-driven migration of inflammatory cells has been implicated in the pathogenesis of atherosclerotic conditions including peripheral arterial disease (PAD). Monocyte chemoattractant protein-1 (MCP-1) is elevated in patients with coronary artery disease and in hypertensive patients. This study therefore investigated MCP-1 in patients with PAD.

Keywords

• Monocyte chemoattractant protein-1
• CC chemokine ligand 2
• Atherosclerosis
• Artheritis obliterans
• Risk factors
• Low-density lipoprotein.