Clinical Ophthalmology (Jul 2022)

Functional Outcome After Macular Hole Surgery: Comparison of Standard Perimetry with Microperimetry

  • Wons J,
  • Pfister IB,
  • Anastasi S,
  • Steinhauer S,
  • Niderprim SA,
  • Garweg JG

Journal volume & issue
Vol. Volume 16
pp. 2235 – 2243

Abstract

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Juliana Wons,1 Isabel B Pfister,1,2 Stefano Anastasi,1 Sonja Steinhauer,1 Sophie-Alexia Niderprim,3 Justus G Garweg1,2,4 1Clinic for Vitreoretinal Disease, Berner Augenklinik, Bern, Switzerland; 2Swiss Eye Institute, Rotkreuz, Switzerland; 3Ophthalmology Private Practice, Langnau, Switzerland; 4Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandCorrespondence: Justus G Garweg, Berner Augenklinik, Bremgartenstrasse 119, Bern, CH-3012, Switzerland, Tel +41 31 311 12 22, Fax +41 31 311 14 33, Email [email protected]: To compare the predictive value of macular perimetry and microperimetry for visual outcomes after vitrectomy with internal limiting membrane (ILM) peeling in full-thickness macular holes (MH).Methods: This retrospective, non-randomized case series refers to 100 eyes undergoing vitrectomy with ILM peeling. Best-corrected visual acuity (BCVA), standard 12° perimetry and microperimetry were perioperatively recorded. A possible predictive value of the preoperative findings on postoperative visual function (PVF) was assessed.Results: Independent of the preoperative minimal MH size (range: 55– 752 μm), all 100 MHs were closed. BCVA improved from 56.3 ± 12.8 to 74.8 ± 9.2 Early Treatment of Diabetic Retinopathy Study (ETDRS) letters after six months and retinal fixation stability enhanced. We found a positive correlation between BCVA and macular sensitivity 6 months postoperatively in microperimetry (r = 0.48, p < 0.010) and 12° perimetry (r = 0.45, p < 0.014), as well as with mean defect (r = 0.48, p < 0.01 and r = 0.44, p < 0.017, respectively). A correlation between preoperative visual function indices and PVF was not established.Conclusion: Microperimetry and standard perimetry are equally suitable for describing perioperative retinal function in idiopathic MH. While the indices of both methods correlate comparably well with BCVA, they cannot predict PVF. This may be partially explained by the area covered by perimetry, compared to which the size of the MH is of inferior relevance.Keywords: central visual field, idiopathic full-thickness macular hole, microperimetry, peeling of the internal limiting membrane, vitrectomy

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