Successful yolk-sac tumor treatment with fertility-sparing partial oophorectomy

Abstract

Yolk-sac tumors account for about 20% of ovarian germ cell tumors and occur predominantly in women below 35 years of age. Modern evidence-based treatment strategies have ensured long term post-treatment survival, but with increased survival, attention has been turned to an urgent need for developing fertility sparing treatment strategies. In this report we describe the successful treatment of a young woman who was able to conceive and deliver two children, in spite of the loss of one ovary two years prior to being diagnosed with an ovarian yolk-sac tumor on the remaining ovary. Keywords: Yolk-sac tumor (YST), Ovarian germ cell tumor, Ovarian cancer, Fertility preservation